Biomimetic Nanoparticle Applications for Treatment of Atherosclerosis

Abstract: 

Atherosclerosis is the leading cause of myocardial infarctions, or heart attacks. To combat atherosclerosis, current regenerative medicine and tissue engineering research focuses on using nanoparticles to repair damaged arteries. Of the various types of nanoparticles, researchers have paid special focus on biomimetic nanoparticles for their long circulation times and ability to evade the immune system. Current treatment options for atherosclerosis contribute to disease management and symptom relief, but they fall short of regenerating the damaged vascular wall. Animal studies using biomimetic nanoparticles have shown promising results, but clinical trials lack the same level of enthusiasm. Continued research and innovative approaches toward nanoparticles hold great potential for transforming and improving patient outcomes. This review aims to establish a concrete understanding of the various biomimetic nanoparticle applications to atherosclerosis treatment.