Bridging Horizons
innovation, Identity and Global Futures
Volume 1, Issue 3 — March 2026
Published July 2026
ISSN: 3069-8200
The Princeton Journal of Interdisciplinary Research (PJIR) proudly presents Volume 1, Issue 3 (2025), Bridging Horizons: Innovation, Identity, and Global Futures — the third installment of our inaugural publishing year.
Building upon the foundations of Voices in Convergence and Frontiers of Inquiry, this issue deepens PJIR’s commitment to rigorous, cross-disciplinary scholarship that confronts both emerging and enduring global questions. The research featured in this edition traverses scientific innovation and technological transformation; re-examinations of social, cultural, and political identities; ethical dimensions of public policy and governance; and evolving intersections between health, economics, and global development.
Two Best Paper selections exemplify this breadth: "Deepfakes On Trial: A Mixed-Methods Study of Student Perceptions and Regulatory Concerns about Non-Consensual Deepfakes at the London School of Economics and Political Science," which interrogates the ethical and regulatory implications of emerging synthetic media technologies. Meanwhile, "Interpretable Transfer Learning with EfficientNetB0 for Automated Detection of Rare Anemia Morphologies in Peripheral Blood Smears" demonstrates how advances in machine learning and biomedical imaging can be translated into clinically meaningful diagnostic tools, highlighting the growing convergence of computational innovation and medical practice.
Alongside the two Best Paper selections, this volume features contributions addressing religion and social meaning, structural inequality, developments in the life sciences, and more. We hope these studies encourage readers to draw connections across fields and to approach complex contemporary questions with intellectual openness.
All accepted articles are published online under ISSN 3069-8200.
Editor’s Note
Serious scholarship often begins with a single, well-defined question. Yet the moment we follow that question far enough, we find it rarely stays in one place. Questions about attention become questions about education and equity. Questions about algorithms become questions about trust and accountability. Questions about biological systems quickly intersect with questions about human experience. This issue brings together work that reflects precisely this movement across boundaries.
In this volume, we are proud to feature research on ADHD, the effects of racial bias in dermatology datasets on convolutional neural networks, the emerging legal terrain of deepfakes, sustainable building materials, structural inequality, developments in the life sciences, and more. The issue also includes work engaging questions of religion and belief, examining gender and social identity, and exploring problems in linguistics, and more.
We celebrate interdisciplinary scholarship not as a slogan, but as a practice. The work collected here demonstrates careful technical reasoning alongside ethical awareness and social sensitivity. It shows that strong research does not dilute disciplinary rigor; rather, it is often strengthened when scholars remain attentive to the wider implications of their methods and findings.
PJIR Editorial Team
Articles in This Issue
The Phenotypic and Functional Diversity of Tissue Tregs, and Their Role in Chronic Viral Infections
Author: Diya Shetty
Affiliation: Neev Academy
Abstract:
Regulatory T cells (Tregs) are a subset of CD4+ T cells characterized by the expression of the transcription factor FoxP3. While Tregs are known to suppress immune cells to mediate immune responses, they exhibit location-specific functions across lymphoid and non-lymphoid tissues. This review examines the factors that influence location-specific functions of Treg phenotypes...
Keywords: Immunity, Tregs, Tissue-specific, Chronic
Liposomal Applications in Imaging and Drug Delivery: A Review
Author: Jai H. Patel¹, Hazal Gezmis Gokce²
Affiliation: ¹Cambridge Centre for International Research
²Department of Materials, 16 Parks Road, University of Oxford, OX1 3PH, UK.
Abstract:
Liposomes have been applied in different biomedical applications, imaging models, and drug delivery. This review shows that the liposomes act as MRI contrast agents and photoluminescent imaging agents with features of magneto-liposomes (MLs) and aminefunctionalized nanodiamonds (NDs)...
Keywords: liposome, magneto-liposomes, nanodiamonds, drug delivery, cancer
A Study on The Impact of Macroeconomic Variables on The Capital Structure of Startups
Author: Dhanya Ganesh
Affiliation: Basis Independent Fremont, California
Abstract:
This research paper examines how macroeconomic parameters influence the capital structure decisions of startup firms, filling a critical gap in the literature where previous studies have primarily focused on firm-specific variables. While prior research on startup financing has predominantly analyzed firm-specific variables...
Keywords: macroeconomic, capital structure, interest rates, unemployment, inflation
Early Detection of Alzheimer’s Risk Through APOE ε4-Linked Blood Protein Changes
Author: Sruthi Chetput
Affiliation: Lynbrook High School
Abstract:
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that begins years before clinical symptoms start to appear. This study investigated whether carriers of the Apolipoprotein E4 (APOE ε4) allele exhibit early changes in plasma protein expression, independent of any amyloid deposition or any cognitive decline...
Keywords: Alzheimer’s, APOE ε4, protein expression, blood-based biomarkers, early detection
Citation for This Issue
Princeton Journal of Interdisciplinary Research. (2026). Volume 1, Issue 3 — Bridging Horizons. PJIR.
https://www.princeton-press.com/pjir/issues/vol-1-issue-3
Open Access Statement
This journal is fully open access. All articles are freely available to read, download, and share without subscription or access barriers. We encourage scholars to cite and engage with the research published here, as such scholarly exchange plays an important role in supporting emerging and early-career researchers and advancing ongoing academic conversations.